Selection of mutants
Selection of mutants: In a patient’s body or in culture, a mutant will become sufficiently numerous to be observable and to produce significant effects only if its new character makes it better fitted to grow under prevailing conditions (in culture medium or host’s tissue) than parental bacteria and so enable it to outgrow an outnumber the latter. Thus mutation is significant only when conditions are selectively favourable to the mutant and bring about its natural or artificial selection. An antibiotic resistant mutant, will outgrow the sensitive parental bacteria in a culture media containing antibiotics or in the body of patient receiving antibiotic therapy.
Tags: carcinomatosis, coronary occlusion, glomerulonephritis, malaria, nephrosis, Rheumatic Fever, serum sickness
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