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STREPTOCOCCUS PYOGENES: Toxin Production

Written by Dr.Chris

Toxin production:
(1) Hemolysins: It is filterable toxic substances. It is of two types:
(a) Streptolysin 0, which is oxygen labile, heat labile, strongly antigenic, important in contributing to virulence (intravenous injec-tion into animal has specific cardiotoxic activity and it is inhibited by cholesterol).
(b) Streptolysin S is oxygen stabile, non antigenic, inhibited non specifically by serum lipoprotein and may […]


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GENETICS

Written by Dr.Chris

GENETICS: Genetics is the study of heredity and variation. The hereditary characters are maintained under the influence of bacterial genes. Genes correspond to specific segment of deoxyribonucleic acid (DNA) molecules of bacterial nucleus. Bacteria contains about 1000 genes or so. Genes are located in circular chromosome of bacteria. The book of information contained is genome, […]


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Chemotherapeutic Agents

Written by Dr.Chris

Chemotherapeutic Agents: These are the agents which have lethal or inhibitory effect on the microbes responsible, but in therapeutic concentration have little or no toxic action on the tissues.
However these agents used in chemotherapy are of very diverse chemical structure. They can be divided into two categories:
(a) Relatively simple compounds obtained by laboratory synthesis e.g., sulfonamides, […]


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Puerperal Infecting organisms

Written by Dr.Chris

Infecting organisms: These include Streptococcus (hemolytic, non-hemolytic, aerobic or anaerobic), Staphylococus aureus. Bacillus coli, Clostridium welchii and occasionally other organisms like Bacillus tetanus. The commonest of these are Streptococcus (hemolytic and non-hemolytic), B. coli and Staphylococcus. Anaerobic streptococci, a normal inhabitant of the vagina, may in the presence of damaged tissue take on pathogenic […]


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