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Prophylaxis

Written by D C Morgan

(a) Irregular and indiscriminate use of penicillin should be avoided. Use it only when it is really indicated
(b) Avoid using penicillin and antihistamine skin ointments
(c) A patient allergic to penicillin should avoid milk from a cow treated with penicillin. Similarly, food materials-bread, cheese etc-contaminated with mould should be avoided.
(d) As far as possible avoid penicillin […]


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Pencillin Sensitisation tests, Scratch Test

Written by D C Morgan

Sensitisation test: There are no reliable sensitisation tests which ca n infallibly predict the occurance of immediate type of reaction to a non protein drug nor is it safe to perform ID tests with suspected drugs as they may sometimes cause severe and even fatal anaphylaxis.
Potassium benzyl penicillin is an excellent antigenic substance which in […]


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Clinical Manifestations of allergic reactions to Penicillin

Written by D C Morgan

The incidence of allergic reactions to penicillin vary from 1 to 10%. One report indicates that five out of 65 venereal disease patients were sensitive to penicillin. Anaphylactic shock occurs in 0.1% of patients who are sensitive. Fever is the commonest reaction.
Anaphylactic shock, serum sickness type reaction (urticaria, fever, joint swelling, angioedema, lymphadenopathy, proteirturia and […]


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How people get sensitised to drugs

Written by D C Morgan

Some patients who develop an allergic response to penicillin do not give history of receiving penicillin in the past. Unknowingly, any body can be sensitised to that drug, by different means. Use of penicillin and antihistamine skin ointments, intake of foods- bread, cheese etc-contaminated by penicillium moulds, contact of penicillin by medical personnels -nurses, doctors, […]


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