Vascular Reactions: Erythema
Written by D C MorganErythema is the dialatation of the dermal capillaries and other vascular structures, by various causes results in reddish coloration of the skin. It can be localised or generalised. Generalised erythema may be produced by various toxins produced during infections.
Toxic erythema may he produced by drugs also. Food allergy,pregnancy and internal malignancy(leukemia,lymplionia) also may produce generalised […]
Tags: cortciosteroids, Generalised erythema, leukemia, lymplionia, pheochromocytoma, Psoriasis, Skin Infection, syndrome, Toxic erythema
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Vesiculo Bullous Dermatoses
Written by D C Morgan Pemphigus Vegetans:- Here, the lesions on flexures of axilla, groin, neck etc undergo hypertrophy producg vegetative lesions.
Pemphigus follaceus:- Here the blisters are very. superficial and on rupture leaves scaling. When generalised, it may produce a […]
Tags: cortciosteroids, Pemphigoid, Pemphigus erythematosus, Pemphigus follaceus, Pemphigus Vegetans, Psoriasis, Skin Infection, Treatment of pemphigus
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Psoriasis: Pemphigoid
Written by D C MorganPemphigoid is more common in elderly people. The blisters are tense and there is often a tendency for spontaneous healing of erosions. Only in one third cases mucous membranes are involved. Tzanck test does not show any acantholytic cells.
Histology reveals a subepidermal bulla. All cases of pemphigoid should be investigated thoroughly to exclude any underlying […]
Tags: cortciosteroids, Psoriasis, Skin Infection, Tzanck test
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Psoriasis: Treatment of pemphigus
Written by D C MorganThe Treatment of pemphigus starts with a high dose of corticosteroid is to be given in all cases, to start with. Once the lesions are controlled, most cases need maintainance dose.
The steriods here act as antiinflammatory and immunosuppressive agent. Cyclophosphamide (endoxan)also have been tried here, as an immunosuppresive.
Repeated blood or plasma tranfusion may be needed […]
Tags: cortciosteroids, Cyclophosphamide, Pemphigus, Psoriasis, Skin Infection
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Psoriasis: Pemphigus Vulgaris
Written by D C MorganPemphigus Vulgaris:- This is characterized by the development of multiple bullae on the skin and mucous membranes. It is an autoimmune disease. Antibodies are produced by the body against the intercellular material of the prickle cells of the epidermis resulting in lysis of intercellular bridges. This causes rounding of the prickle cells and formation of […]
Tags: Bulla spread, Intraepidermal blisters, Psoriasis, Skin Infection, Tzanck test
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Lichen striatus and Pityriasis Rubra Pilaris
Written by D C MorganLichen striatus These are usually seen in children. It presents as multiple closely set lichenoid papules arranged in linear streaks On the limbs and occasionally on trunk. The length of the lesion may vary from 10 to 20 cm. The cause of this condition is uncertain.
It may persist for a few months. Topical corticosteroid may […]
Tags: follicular papules, keratoderma, Psoriasis, Skin Inection
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Exfoliative Dermatitis
Written by D C MorganThis is a condition characterised by generalised erythema and scaling. The common causes of exfoliative dermatitis are skin diseases like psoriasis, seborrhoeic dermatitis, pityriasis rubra pilaris, Norwegian scabies and chronic eczematous dermatitis with autosensitisation. It can sometimes he the external manifestation of an underlying malignancy especially lymphomas like Hodgkin’s disease and mycosis fungoides.
Occasionally drugs like […]
Tags: mycosis fungoides, Psoriasis, Skin Infection
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Lichen Nitidus and Parapsoriasis
Written by D C MorganLichen nitidus Tiny, Shiny, pinhead sized, grouped papules appear on the forearms, abdomen:and male genitalia. The exact cause of this disease is not certain. Histology shows a granulomatous infiltration in the upper dermis. Usually it lasts for a few months. Treatment consists of application of corticosteroid ointment.
Parapsoriasis Guttate parapsoriasis usually appears as scaly papules on […]
Tags: corticosteroid, cutaneous lymphomas, mycosis fungoides, Psoriasis, Skin Infection, skin lesions
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Pityriasis Rosea
Written by D C MorganThis is characterised by development of a self limiting eruption on the bathing suit areas of body (trunk and proximal parts of limbs). it is usually preceded by a large scaly plaque called herald patch.
The eruption consists of multiple oval macules and papules with collarette scales and ash like pigmentation in the centre of each […]
Tags: antihistamines, Psoriasis, Skin Infection
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Psoriasis: Lichen Planus
Written by D C MorganIt is characterized by development of intensely pruritic, violaceous colored polygonal papules on the front of forearms and legs. isomorphic lesions may develop on lines of trauma, thus showing Koebner phenomenon.
Oral lesions include lace like whitish streaks and papules on mucous membranes of cheeks, tongue and lips. Some times hypertrophic lesions may develop on legs. […]
Tags: corticosteroid, Hypertrophic lesions, Koebner phenomenon, Oral lesions, Psoriasis, Skin Infection
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Indications for corticosteroids in Psoriasis
Written by D C MorganThere are only a few indications for corticosteroids in psoriasis. They are, severe mutilating arthropathy, severe exfoliative dermatitis that does not respond to other measures and severe generalised pustular psoriasis. Steroid in psoriasis gives dramatic improvement. But once the dose is lowered, rebound phenomenon occurs and severe exfoliation results. Topical steroids are indicated only for […]
Tags: Corticosteroids, Psoriasis, Skin Infection, Steroid in psoriasis
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Systemic drugs for psoriasis
Written by D C MorganThere are mainly three drugs for this purpose in psoriasis. They are methotrexate, psoralen and corticosteroids. Methotrexate is an antimetabolite mainly used in cancer therapy. Just like malignancy, in psoriasis also there is an uncontrolled. multiplication of cells. This drug inhibit the enzyme dihydro and tetrahydrofolate reductase, thereby formation of tetrahydrofolate (citrovaruin factor) is interfered. […]
Tags: Corticosteroids, Methotrexate, Mitosis, Psoralen, Psoriasis, Skin Infection
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Papulo squamous disorders
Written by D C MorganPsoriasis is a common skin disorder characterized by focal, benign, epidermal hyperplasia. The actiology of this disease is still not certain. In 25 to 30% of cases there may be a family history of similar. disease. Clinically it presents as multiple, well defined, raised lesions on top of which abundant, loose, dry, white, micaceous scales […]
Tags: Auspitz sign, epidermal hyperplasia, Koebner phenomenon, Psoriasis, Skin Infection
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Different types of Psoriasis
Written by D C Morgan Typical (extensor) Psoriasis:- Classically in psoriasis the lesions are distributed on the scalp,knees and lu:nbosacral areas.
Flexural type:- Here the lesions are more on flexures of body like axillae and groin and they tend to he […]
Tags: Exfoliative psoriasis, Guttate Psoriasis, Psoriasis, Psoriatic arthropathy, Pustular psoriasis
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Topical medicines for Psoriasis
Written by D C MorganTopical medicines for Psoriasis include coaltar, dithranol, Aliimoniated mercury and salicylic acid. Coaltar is available in its crude form or as semisolid form (ichthamol) and liquid form (liquor picis carb). It is usually given in 3 to 10% strength in Vaseline with or without adding other antipsoriatic agents. Ammoniated mercury, another antipsoriatic agent is a […]
Tags: Anthralin, Dithranol, Protoplasmic Poison, Psoriasis, Psoriasis Treatment, Skin Infection
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