Gontroccal volvo vaginitis
Written by Dr.ChrisGontroccal volvo vaginitis:- The stratified squamous epithelium of adult vagina is resistant to the invasion by gonococci.
So vaginitis is usully not produced by gonococci in adults. But in young girls goncocci can cause acute vulvovaginitis which presents as acutely painful swelling of the vulva and vagina with discharge.
Tags: Skin Infection, STD
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Leprosy (Hansen’s disease)
Written by Dr.ChrisLeprosy (Hansen’s disease) is a chronic infectious disease caused by an acid fast bacillus called Mycobacterium leprae. These organisms are seen in clumps in tissue smears and are less acid fast and less alcohol fast than mycobacterium tuberculosis, the causative organism for tuberculosis. In vitro culture of the organism is still not successful; even though […]
Tags: Dermatology, leprosy, Skin Infection
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SKIN IN SYSTEMIC DISEASES
Written by D C MorganSkin often mirrors the presence of an internal disease. A detailed dermatological examination often helps the physician to get some clues regarding the primary disease from which the patient is suffering.
Skin and gastrointestinal tract:- Most of the gastrointestinal diseases are associated with some form of skin lesions. In Peutz-Jeghers syndrome intestinal polyps are associated wtih […]
Tags: Dermatology, Gardner s syndrome, Peutz-Jeghers syndrome, Skin Infection, steatorrhoea
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Dermatomyositis
Written by D C MorganThe first symptom noticed by most of the patients with dermatomyositis is difficulty to climb up steps. The proximal group of muscles of the limb; are affected first by the disease process. Tenderness of the muscle may be elicited in most cases.
Skin changes include diffuse erythema, inac.ulopapular eruptions and exfoliative dermatitis. Heliotropic pigmentation in the […]
Tags: Dermatology, sclerodermatomyositis, Skin Infection, SLE
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Chloracne
Written by D C MorganConstant exposure to cutting oil, lubricating oil etc. containing chlornaphthalene often leads to the development of acniform lesions on the skin especially on the forearms. This is known as chloracne or industrial acne. This is commonly Observed in people working in motor workshops.
Tags: Acne, industrial acne, Skin Infection
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Treatment of acne
Written by D C MorganAcne is a chronic inflammatory disorder of pilosebaceous apparatus. At the time of puberty there is an increased level Of androgens in body. This androgen causes increase in size and activity of sebaceous glands. It further causes epithelialisation of-follicular orifices which leads to partial block in the follicular opening. This block and subsequent anoxia leads […]
Tags: Dermatology, Skin Infection
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Half Half Nails
Written by D C MorganHalf Half Nails is a recently described change in the nails of patients with chronic renal failure with high blood urea levels. The proximal half of the nail is white and the distal half remains pink, red or brown.
There is always a sharp demarcation between the two halves. The incidence and pathophysiology of ‘half half’ […]
Tags: chronic renal failure, demarcation, high blood urea, Skin Infection
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Merits and Demerits of Various in Vivo Tests
Written by D C MorganA positive skin test in itself does not indicate absolutely that the patient will develop systemic reaction upon receiving penicillin and a negative test does not mean that penicillin can be administered safely.
The possibility that routine skin testing with penicillin may itself lead to sensitisation is there. The scratch test though easy to perform is […]
Tags: Dermatology, ID test, Negative Skin Test, Positive Skin Test, Skin Infection, Subcutaneous Test
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Infra Dermal (ID) Test
Written by D C MorganIn Infra Dermal (ID) Test, 0.1 ml of the test solution of penicillin is injected intradermally on the forearm and mark the area with a skin pencil. Development of a flare and wheal at that site with in 15 to 20 minutes indicates sensitivity.
A patient on test dose, should not receive any corticosteroid or antihistamines […]
Tags: Anaphylaxis, Dermatology, ID test, Skin Infection
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How people get sensitised to drugs
Written by D C MorganSome patients who develop an allergic response to penicillin do not give history of receiving penicillin in the past. Unknowingly, any body can be sensitised to that drug, by different means. Use of penicillin and antihistamine skin ointments, intake of foods- bread, cheese etc-contaminated by penicillium moulds, contact of penicillin by medical personnels -nurses, doctors, […]
Tags: allergy, Drug Allergy, Histamine, Pencillin Allergy, Rheumatic Fever, Skin Infection
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Penicillin Allergy: Immunology and pathogenesis
Written by D C Morgan:- According to the present evidences there are at least 6 antigenic determinents in penicillin allergy. The major antigenic determinent is the penicilloyl group which can form by the direct reaction of penicillin with protein. Other intermediates in the formation of antigen includes 6-aminopenicillanie acid and penicilloic acid. Patients with penicillin allergy usually exhibits immediate […]
Tags: allergy, antidote, penicillin allergy, polylysine, Skin Infection
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ALLERGIC REACTIONS TO PENICILLINS
Written by D C MorganIn 1940 Chain, Florey and others succeeded in producing the first penicillins from the cultures of penicillium notatum. Though, day by day newer and newer drugs-both static and cidal-are introduced to fight against the bacteria, penicillin remains still the best, at the same time cheap, bactericidal drug.
The only draw back is the severe anaphylaxis which […]
Tags: cultures of penicillium notatum, Florey, penicillin therapy, Skin Infection
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Teratogenic effect, Hypersensitivity
Written by D C MorganTeratogenic effect: - Developmental defects may be produced in the foetus by administration of certain drugs especially between the 34th and 45th days of gestation. Methotrexate, tetracycline, corticosteroids, phenothiazines and thalidomides are the common teratogenic agents.
Hypersensitivity:- There are mainly four types of hypersensitivity reactions. They are: Type I Anaphylaxis Type II Cytotoxic Type III Arthus; […]
Tags: Anaphylaxis, Arthus; serum sickness, Corticosteroids, Cytotoxic, Dermatology, Methotrexate, Skin Infection, teratogenic agents, tetracycline
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Erytheme multiforme
Written by D C MorganErytheme multiforme manifests as sudden eruption of different types of lesions-erythema, papules, nodules, plaques, vesicles and bullae. The lesions are distributed bilaterally on the flexor aspect of the distal part of limbs. The characteristic lesion seen in erythema multiforme is called ‘iris lesion’. It presents as an erythematous, round macule or plaque.
The central part of […]
Tags: Dermatology, Iris lesion, Skin Infection, Stevens Johnson syndrome, Vascular Reactions
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Toxic epidermal necrolysis
Written by D C MorganToxic epidermal necrolysis is a severe condition characterized by sudden development of superficial blisters which join in a few hours, to form ’scald’ like skin lesions. The epidermis gets detached in sheets to leave large raw areas.
Drugs and staphylococcal toxins are the main causes of this often fatal condition. The patient will be highly toxic. […]
Tags: Dermatology, Skin Infection, skin lesions, staphylococcal toxins, Vascular Reactions
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