CLINICAL FEATURES OF HEPATIC PRECOMA
Written by Dr.ChrisClinical Features: The earliest symptoms are behavioural changes, impaired memory, slurred speech and a disturbed sleep rhythm. These are usually followed by confusion, apathy and drowsiness or iritability and restlessness (precoma). A characteristic ‘liver flap’ (asterixis) is often demonstrable and has been ascribed to impaired inflow of joint and posture afferent information to the reticular […]
Tags: ankle oedema, ascites, palmer erythema, prominent collaterals, splenomegaly
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Serum Sickness
Written by Dr.ChrisSerum Sickness: This is a systemic form of type III hypersensitivity. It appears 7 to 12 days following single injection of high concentration of foreign serum like diphtheria antitoxin. Clinical manifestations are fever, lymphadenopathy, splenomegaly, arthritis, glomerulonephritis, endocarditis, vasculitis, urticarial rash, abdominal pain, nausea and vomit¬ing. The pathogenesis is the formation of immune complex (foreign […]
Tags: abdominal pain, Arthritis, endocarditis, glomerulonephritis, lymphadenopathy, nausea, splenomegaly, urticarial rash, vasculitis
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